Research - DaiLab

Synthetic yeast from 2.0 to 3.0

2017-11-09

The Synthetic Yeast Genome Project (Sc2.0) is the world’s first synthetic eukaryotic genome project that aims to create a novel, rationalized version of the genome of the yeast species Saccharomyces cerevisiae. We have a better understanding of how yeast genome works after synthesizing yeast genome. Based on what we learned from Sc2.0, we are aiming to re-design a yeast genome with well-known......

Genome Project-write

2017-11-09

The Genome Project-write (GP-write) is an open, international research project, which includes whole genome engineering of human cell lines and other organisms of agricultural and public health significance. GP-write will use synthesis and genome editing technologies to understand, engineer and test living systems. It will build on the knowledge and technological advances of HGP-read......

Epigenetics

2017-11-09

Epigenetics is part of a field of genetics-"epi" coming from the Greek for "over, on top of". Epigenetics is an additional layer of instructions that lies "on top of" DNA, controlling how the genes are read and expressed. We have established versatile histone H3/H4 and H2A/H2B mutant library in yeast to study histone related DNA-damage response, genome stability and synthetic lethal interactions.....

Plant Artificial Chromosome

2024-11-22

A plant artificial chromosome (PAC) is a de novo synthesized DNA molecule that replicates and functions as an additional chromosome within a plant cell. PACs provide a stable platform for the introduction, modification, or deletion of specific genes in abundance. This technology allows researchers to incorporate large segments of DNA, facilitating the expression of multiple genes or complex pathwa...

Researches

Synthetic yeast from 2.0 to 3.0

Genome Project-write

Epigenetics

Plant Artificial Chromosome

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